Recombinant Human Glutathione transferase zeta 1, His-tagged GSTZ1-1947H

Recombinant Human Glutathione transferase zeta 1, His-tagged

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Recombinant Human Glutathione transferase zeta 1, His-tagged

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Cat. No. : GSTZ1-1947H
Product Overview : Recombinant GSTZ1 protein fused to his-tag was expressed inE.coliand purified by using conventional chromatography techniques, 26.2 kDa (236aa).
Description : GSTZ1, also known as maleylacetoacetate isomerase, is an enzyme that belongs to glutathione S-transferase (GSTs) super-family. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. It also plays a significant role in the catabolism of phenylalanine and tyrosine.
Source : E.coli.
Purity : > 95% by SDS – PAGE.
Physical Appearance : Liquid.
Formulation : In Phosphate Buffered Saline pH7.4 containing 10% glycerol.
Concentration : 1.0 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE ETRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Drug metabolism - cytochrome P450; Glutathione metabolism; Metabolic pathways; Metabolism of xenobiotics by cytochrome P450; Tyrosine metabolism; Metabolism of amino acids and derivatives
PDB rendering based on 1fw1. :

Gene Name : GSTZ1 glutathione transferase zeta 1 [ Homo sapiens ]
Synonyms : GSTZ1; glutathione transferase zeta 1; MAI; MAAI; GSTZ1-1; MGC2029; maleylacetone isomerase; maleylacetoacetate isomerase; glutathione S-aryltransferase; glutathione S-alkyltransferase; glutathione S-aralkyltransferase; glutathione s-transferase Zeta 1; S-(hydroxyalkyl)glutathione lyase; EC 5.2.1.2,EC 2.5.1.18
Gene ID : 2954
mRNA Refseq : NM_001513
Protein Refseq : NP_001504
MIM : 603758
UniProt ID : O43708
Chromosome Location : 14q24.3
Function : glutathione peroxidase activity; glutathione transferase activity; isomerase activity; maleylacetoacetate isomerase activity; protein binding; transferase activity

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