"BPGM" Related Products

Expand
Expand
Expand

Recombinant Human 2,3-Bisphosphoglycerate Mutase, His-tagged

Cat. No. : BPGM-667H
Product Overview : Recombinant human BPGM, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 31kDa (267aa).
Description : Bisphosphoglycerate mutase (BPGM) is an enzyme unique to erythrocytes and placental cells. This protein plays a major role in regulating hemoglobin oxygen affinity as a consequence of controlling 2,3-BPG concentration. It is responsible for the catalytic synthesis of 2,3-Bisphosphoglycerate (2,3-BPG) from 1,3-BPG. BPGM also has a mutase and a phosphatase function, but these are much less active.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
Purity : > 95% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MSKYKLIMLR HGEGAWNKEN RFCSWVDQKL NSEGMEEARN CGKQLKALNF EF D LVFTSVL NRSIHTAWLI LEELGQEWVP VESSWRLNERHYGALIGLNR EQMAL NHGEE QVRLWRRSYN VTPPPIEESH PYYQEIYNDR RYKVCDVPLD QLPRSE SLKD VLERLLPYWN ERIAPEVLRG KTILISAHGN SSRALLKHLE GISDEDIINI TLP TGVPILL ELDENLRAVG PHQFLGDQEA IQAAIKKVED QGKVKQAKKL EHHHHHH.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Crystallographic structure of dimeric human bisphosphoglycerate mutase. :

Gene Name : BPGM 2,3-bisphosphoglycerate mutase [ Homo sapiens ]
Synonyms : 2,3-bisphosphoglycerate mutase; BPGM; bisphosphoglycerate mutase; BPG-dependent PGAM; 2,3-bisphosphoglycerate synthase; erythrocyte 2,3-bisphosphoglycerate mutase; 2,3-bisphosphoglycerate mutase, erythrocyte; OTTHUMP00000207869; EC 5.4.2.4,EC 5.4.2.1,EC 3.1.3.13
Gene ID : 669
mRNA Refseq : NM_001724
Protein Refseq : NP_001715
MIM : 222800
UniProt ID : P07738
Chromosome Location : 7q31-q34
Pathway : Glycolysis / Gluconeogenesis; Metabolic pathways
Function : 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity; bisphosphoglycerate mutase activity; hydrolase activity; isomerase activity; phosphoglycerate mutase activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.