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Recombinant Human RRAS, His-tagged

Cat.No. : RRAS-2360H
Product Overview : Recombinant human RRAS protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 25.3 kDa (235aa).
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  • Gene Information
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Cat. No. : RRAS-2360H
Description : RRAS, also known as ras-related protein R-Ras, belongs to the Ras family which functions in signal transduction pathways. This protein has been shown to interact with RASSF5, NCK1, Bcl-2, ARAF and RALGDS. RRAS can bind GTP and GDP, and it has intrinsic GTPase activity. It also regulates the organization of the actin cytoskeleton.
Source : E.coli.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
Purity : > 85% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVV VGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKICSVDGIPARLD ILDT AGQ EEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAFGASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKY QE QELPP SPPSAPRKKG GGCPC.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : RRAS related RAS viral (r-ras) oncogene homolog [ Homo sapiens ]
Synonyms : related RAS viral (r-ras) oncogene homolog; RRAS; ras-related protein R-Ras; p23; Oncogene RRAS
Gene ID : 6237
mRNA Refseq : NM_006270
Protein Refseq : NP_006261
MIM : 165090
UniProt ID : P10301
Chromosome Location : 19q13.3-qter
Pathway : MAPK signaling pathway; Regulation of actin cytoskeleton; Tight junction; Axon guidance
Function : protein binding; nucleotide binding; GTPase activity; GTP binding; GDP binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do alterations in RRAS expression or activity affect tumorigenesis and cancer therapy response? 09/06/2021

Variations in RRAS can influence cancer development and affect how cancer cells respond to therapies.

What is the impact of RRAS on angiogenesis and vascular remodeling? 05/04/2020

RRAS affects angiogenesis and vascular remodeling, crucial for tissue growth and repair.

What role does RRAS play in cell adhesion and migration, particularly in cancer metastasis? 03/08/2020

RRAS is involved in cell adhesion and migration, playing a significant role in cancer cell metastasis.

How does RRAS influence immune cell activation and the immune response? 01/23/2020

RRAS modulates immune cell activation, impacting the overall immune response.

What are the mechanisms by which RRAS modulates cellular proliferation and differentiation? 01/08/2020

RRAS controls cellular processes like proliferation and differentiation, essential for normal development and tissue maintenance.

How does RRAS contribute to the development and progression of cardiovascular diseases? 04/06/2019

RRAS contributes to cardiovascular diseases by influencing cell signaling pathways in heart and blood vessel cells.

How does RRAS (Related RAS Viral (R-Ras) Oncogene Homolog) influence signal transduction pathways in cells? 02/13/2018

RRAS regulates various signal transduction pathways, affecting cell growth, survival, and differentiation.

Customer Reviews (3)

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Reviews
08/30/2021

    Precise protein quantification, fundamental for data accuracy in our experiments.

    01/07/2019

      Dependable peptide synthesis, accelerates our peptide-focused projects effectively.

      01/06/2019

        Timely antibody validation, a valuable asset for our laboratory.

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