"SGTA" Related Products

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Recombinant Human SGTA, His-tagged

Cat. No.: SGTA-2359H
Product Overview: Recombinant human SGTA protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 35.1 kDa (321aa).
Description: SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances.
Source: E.coli.
Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
Purity: > 95% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEEDSAE AERLKTEGNE QMKVENFEAA VHFYGKAIEL NPANAVYFCN RAAAYSKLGN YAGAVQDCER AICIDPAYSK AYGRMGLALS SLNKHVEAVA YYKKALELDP DNETYKSNLK IAELKLREAP SPTGGVGSFD IAGLLNNPGF MSMASNLMNN PQIQQLMSGM ISGGNNPLGT PGTSPSQNDL ASLIQAGQQF AQQMQQQNPE LIEQLRSQIR SRTPSASNDD QQELEHHHHH H.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha [ Homo sapiens ]
Synonyms: SGTA; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; SGT; hSGT; alphaSGT; small glutamine-rich tetratricopeptide; protein containing three tetratricopeptide repeats
Gene ID: 6449
mRNA Refseq: NM_003021
Protein Refseq: NP_003012
MIM: 603419
UniProt ID: O43765
Chromosome Location: 19p13
Function: protein binding

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