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Recombinant Human UBE2T, His-tagged

Cat.No. : UBE2T-2355H
Product Overview : Recombinant human UBE2T protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 23.6 kDa (205aa).
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Cat. No. : UBE2T-2355H
Description : UBE2T, also known as PIG50 or HSPC150, is a member of the E2 ubiquitin-conjugating enzyme family Involved in the protein degradation pathway. This protein catalyzes the ATP-dependent attachment of ubiquitin (Ub) to target proteins, thereby tagging them for subsequent destruction by the proteasome. Additionally, UBE2T is thought to be a crucial component of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV FK LE VIIPER YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP DDPLMADISS EFKYNKPAFL KNARQWTEKH ARQKQKADEE EMLDNLPEAG DSRVHNSTQK RKASQLVGIE KKFHPDVLEH HHHHH.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : UBE2T ubiquitin-conjugating enzyme E2T (putative) [ Homo sapiens ]
Synonyms : ubiquitin-conjugating enzyme E2T (putative); PIG50; HSPC150; UBE2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-protein ligase T; ubiquitin carrier protein T; ubiquitin conjugating enzyme; cell proliferation-inducing gene 50 protein; HSPC150 protein similar to ubiquitin-conjugating enzyme ; EC 6.3.2.19; Ubiquitin carrier protein T; Ubiquitin-protein ligase T
Gene ID : 29089
mRNA Refseq : NM_014176
Protein Refseq : NP_054895
MIM : 610538
UniProt ID : Q9NPD8
Chromosome Location : 1q32.1
Pathway : DNA Repair
Function : ubiquitin-protein ligase activity; ATP binding; ligase activity; nucleotide binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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03/03/2021

    The performance is reliable and has been tremendously helpful for my experiments.

    12/10/2018

      Utmost confidence is instilled within me due to the steadfast reliability of this reagent.

      11/29/2017

        Extraordinary excellence epitomizes the protein reagents manufactured by you. Commendations!

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