"UBE2T" Related Products

Recombinant Human UBE2T, His-tagged

Cat. No. : UBE2T-2355H
Product Overview : Recombinant human UBE2T protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 23.6 kDa (205aa).
Description : UBE2T, also known as PIG50 or HSPC150, is a member of the E2 ubiquitin-conjugating enzyme family Involved in the protein degradation pathway. This protein catalyzes the ATP-dependent attachment of ubiquitin (Ub) to target proteins, thereby tagging them for subsequent destruction by the proteasome. Additionally, UBE2T is thought to be a crucial component of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MQRASRLKRE LHMLATEPPP GITCWQDKDQ MDDLRAQILG GANTPYEKGV FK LE VIIPER YPFEPPQIRF LTPIYHPNID SAGRICLDVL KLPPKGAWRP SLNIATVLTS IQLLMSEPNP DDPLMADISS EFKYNKPAFL KNARQWTEKH ARQKQKADEE EMLDNLPEAG DSRVHNSTQK RKASQLVGIE KKFHPDVLEH HHHHH.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : UBE2T ubiquitin-conjugating enzyme E2T (putative) [ Homo sapiens ]
Synonyms : ubiquitin-conjugating enzyme E2T (putative); PIG50; HSPC150; UBE2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-protein ligase T; ubiquitin carrier protein T; ubiquitin conjugating enzyme; cell proliferation-inducing gene 50 protein; HSPC150 protein similar to ubiquitin-conjugating enzyme ; EC 6.3.2.19; Ubiquitin carrier protein T; Ubiquitin-protein ligase T
Gene ID : 29089
mRNA Refseq : NM_014176
Protein Refseq : NP_054895
MIM : 610538
UniProt ID : Q9NPD8
Chromosome Location : 1q32.1
Pathway : DNA Repair
Function : ubiquitin-protein ligase activity; ATP binding; ligase activity; nucleotide binding

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