"PIAS1" Related Products

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Recombinant Human PIAS1, GST-tagged

Cat. No.: PIAS1-673H
Description: PIAS1 is a SUMO E3 ligase with specificity for a range of different substrates including p53, Hdm2, transcription factors, androgen receptors and co-repressor proteins.
Source/Host: E.coli.
Biological Activity: Exhibits SUMO modification activity in vitro.
Application: For use in SUMO modification reactions and SUMOylation pathway studies.
Long Term Storage: -80°C.
Gene Name: PIAS1 protein inhibitor of activated STAT, 1 [ Homo sapiens ]
Synonyms:
protein inhibitor of activated STAT, 1; GBP; ZMIZ3; DDXBP1; GU/RH-II; MGC141878; MGC141879; PIAS1; E3 SUMO-protein ligase PIAS1; gu-binding protein; AR interacting protein; DEAD/H box-binding protein 1; RNA helicase II-binding protein; zinc finger, MIZ-type containing 3; protein inhibitor of activated STAT protein 1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; protein inhibitor of activated STAT-1; Gu-binding protein; Protein inhibitor of activated STAT protein 1
Gene ID: 8554
mRNA Refseq: NM_016166
Protein Refseq: NP_057250
MIM: 603566
UniProt ID: O75925
Chromosome Location: 15q
Pathway: Jak-STAT signaling pathway; Pathways in cancer; Small cell lung cancer; Ubiquitin mediated proteolysis
Function: transcription coactivator activity; transcription corepressor activity; DNA binding; SUMO ligase activity; androgen receptor binding; enzyme binding; metal ion binding; protein binding; zinc ion binding

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