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Recombinant Human CD2 Molecule

Cat. No.: CD2-2392H
Product Overview: Recombinant Human CD2 Molecule (25-209 aa) is expressed inE.coli.MW=46kDa.
Description: CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
Source: E. coli.
Presentation: 100μl purified human CD2 protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
Application: ELISA, Inhibition Assays, Western Blotting.
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 46kDa including GST.
Storage: Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: CD2 CD2 molecule [ Homo sapiens ]
Synonyms: CD2; CD2 molecule; T11; SRBC; FLJ46032; CD2 antigen (p50), sheep red blood cell receptor; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; LFA-2; LFA-3 receptor; Erythrocyte receptor; Rosette receptor; CD2 antigen; OTTHUMP00000024366; OTTHUMP00000059318
Gene ID: 914
mRNA Refseq: NM_001767
Protein Refseq: NP_001758
MIM: 186990
UniProt ID: P06729
Chromosome Location: 1p13
Pathway: Cell adhesion molecules (CAMs); Hematopoietic cell lineage; Hemostasis; Signaling in Immune system
Function: eukaryotic cell surface binding; protein binding; protein homodimerization activity; receptor activity

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