Recombinant Human CD2 Molecule

• Cat.No.: CD2-2392H
• Product Overview: Recombinant Human CD2 Molecule (25-209 aa) is expressed inE.coli.MW=46kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 25-209 a.a.
• Description: CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
• Presentation: 100μl purified human CD2 protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
• Application: ELISA, Inhibition Assays, Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 46kDa including GST.
• Storage: Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: CD2 CD2 molecule [ Homo sapiens ]
• Synonyms: CD2; CD2 molecule; T11; SRBC; FLJ46032; CD2 antigen (p50), sheep red blood cell receptor; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; LFA-2; LFA-3 receptor; Erythrocyte receptor; Rosette receptor; CD2 antigen; OTTHUMP00000024366; OTTHUMP00000059318
• Gene ID: 914
• mRNA Refseq: NM_001767
• Protein Refseq: NP_001758
• MIM: 186990
• UniProt ID: P06729
• Chromosome Location: 1p13
• Pathway: Cell adhesion molecules (CAMs); Hematopoietic cell lineage; Hemostasis; Signaling in Immune system
• Function: eukaryotic cell surface binding; protein binding; protein homodimerization activity; receptor activity