"MET" Related Products


Recombinant Human MET

Cat. No.: MET-2394H
Product Overview: Recombinant Human MET(aa 18-217) is expressed inE.coli.MW=50kDa.
Description: The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.
Source: E. coli.
Presentation: 100μl purified human MET protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
Application: ELISA, Inhibition Assays, Western Blotting.
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 50kDa including GST.
Storage: Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: MET met proto-oncogene (hepatocyte growth factor receptor) [ Homo sapiens ]
Synonyms: MET; met proto-oncogene (hepatocyte growth factor receptor); AUTS9; HGFR; RCCP2; c-Met; HGF receptor; OTTHUMP00000069168; SF receptor; met proto-oncogene; met proto-oncogene tyrosine kinase; oncogene MET; scatter factor receptor; EC; HGF/SF receptor; met proto-oncogene
Gene ID: 4233
mRNA Refseq: NM_000245
Protein Refseq: NP_000236
MIM: 164860
UniProt ID: P00533
Chromosome Location: 7q31
Pathway: Adherens junction; Axon guidance; Colorectal cancer; Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Focal adhesion; Melanoma; Renal cell carcinoma
Function: Cell proliferation; cell surface receptor linked signal transduction; multicelllular organismal development; protein amino acid phosphorylation

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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