Recombinant Human Cofilin 1 (Non-muscle), GST-tagged

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Recombinant Human Cofilin 1 (Non-muscle), GST-tagged

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Cat. No. : CFL1-2374H
Product Overview : Recombinant human Cofilin1 (2-end) with N-terminal GST tag, was expressed in aE.coliexpression system. MW=44 kDa.
Description : Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Source : E.coli.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
Application : Kinase substrate for the kinase assay; western blot.
Stability : >6 months at –80°C.
Pathways : Axon guidance; Regulation of actin cytoskeleton; Hemostasis
PDB rendering based on 1q8g. :

Gene Name : CFL1 cofilin 1 (non-muscle) [ Homo sapiens ]
Synonyms : CFL-1; CFL1; CFL; p18; 18 kDa phosphoprotein; Cofilin1; Cofilin-1; 18 kDa phosphoprotein; Cofilin, non-muscle isoform; cofilin 1 (non-muscle)
Gene ID : 1072
mRNA Refseq : NM_005507
Protein Refseq : NP_005498
MIM : 601442
UniProt ID : P23528
Chromosome Location : 11q13
Function : actin binding; protein binding

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