Recombinant Human Cofilin 1 (Non-muscle), GST-tagged

• Cat.No.: CFL1-2374H
• Product Overview: Recombinant human Cofilin1 (2-end) with N-terminal GST tag, was expressed in aE.coliexpression system. MW=44 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 2-end a.a.
• Description: Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
• Application: Kinase substrate for the kinase assay; western blot.
• Stability: >6 months at –80°C.
• Pathways: Axon guidance; Regulation of actin cytoskeleton; Hemostasis

Gene Information

• Gene Name: CFL1 cofilin 1 (non-muscle) [ Homo sapiens ]
• Synonyms: CFL-1; CFL1; CFL; p18; 18 kDa phosphoprotein; Cofilin1; Cofilin-1; 18 kDa phosphoprotein; Cofilin, non-muscle isoform; cofilin 1 (non-muscle)
• Gene ID: 1072
• mRNA Refseq: NM_005507
• Protein Refseq: NP_005498
• MIM: 601442
• UniProt ID: P23528
• Chromosome Location: 11q13
• Function: actin binding; protein binding