"CFL1" Related Products


Recombinant Human Cofilin 1 (Non-muscle), GST-tagged

Cat. No.: CFL1-2374H
Product Overview: Recombinant human Cofilin1 (2-end) with N-terminal GST tag, was expressed in aE.coliexpression system. MW=44 kDa.
Description: Cofilin is a family of actin-binding proteins which disassembles actin filaments. It is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
Source: E.coli.
Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT.
Application: Kinase substrate for the kinase assay; western blot.
Stability: >6 months at –80°C.
Pathways: Axon guidance; Regulation of actin cytoskeleton; Hemostasis
Gene Name: CFL1 cofilin 1 (non-muscle) [ Homo sapiens ]
Synonyms: CFL-1; CFL1; CFL; p18; 18 kDa phosphoprotein; Cofilin1; Cofilin-1; 18 kDa phosphoprotein; Cofilin, non-muscle isoform; cofilin 1 (non-muscle)
Gene ID: 1072
mRNA Refseq: NM_005507
Protein Refseq: NP_005498
MIM: 601442
UniProt ID: P23528
Chromosome Location: 11q13
Function: actin binding; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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