"TNFRSF17" Related Products

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Recombinant Human TNFRSF17 protein, Fc/His-tagged

Cat.No.: TNFRSF17-2348H
Product Overview: Recombinant Human TNFRSF17 fused with Fc/His tag at C-terminal was expressed in HEK293.
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Source: HEK293
Species: Human
Tag: Fc/His
Form: Lyophilized from sterile PBS, pH 7.4
Molecular Mass: The recombinant human TNFRSF17/Fc is a disulfide-linked homodimer. The reduced monomer comprises 302 amino acids after removal of the signal peptide and has a predicted molecular mass of 34 kDa. As a result of glycosylation, the apparent molecular mass of rh TNFRSF17/Fc monomer is approximately 40 kDa in SDS-PAGE under reducing conditions.
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Stability: Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage: Store it under sterile conditions at -20 centigrade~-70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Name: TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [ Homo sapiens ]
Official Symbol: TNFRSF17
Synonyms: TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCMA; tumor necrosis factor receptor superfamily member 17; BCM; CD269; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein;
Gene ID: 608
mRNA Refseq: NM_001192
Protein Refseq: NP_001183
MIM: 109545
UniProt ID: Q02223
Chromosome Location: 16p13.1
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem;
Function: receptor activity; tumor necrosis factor-activated receptor activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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