"FAM3C" Related Products


Recombinant Human FAM3C, FLAG-tagged

Cat. No.: FAM3C-2150H
Product Overview: Recombinant Human ILEI (interleukin-like EMT inducer) (aa 25-227) produced inCHOis fused at the C-terminus to a FLAG-tag, ~25kDa.
Description: ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
Source: CHO.
Concentration: 0.1mg/ml after reconstitution.
Purity: ≥95% (SDS-PAGE).
Formulation: Lyophilized. Contains PBS.
Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Reconstitution: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
Short Term Storage: +4°C.
Long Term Storage: -20°C.
Use/Stability: Stable for at least 6 months after receipt when stored at -20°C.
Handling: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.
Gene Name: FAM3C family with sequence similarity 3, member C [ Homo sapiens ]
Synonyms: family with sequence similarity 3, member C; ILEI; GS3786; FAM3C; interleukin-like EMT inducer; predicted osteoblast protein
Gene ID: 10447
mRNA Refseq: NM_001040020
Protein Refseq: NP_001035109
MIM: 608618
UniProt ID: Q92520
Chromosome Location: 7q31
Function: cytokine activity

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