"BID" Related Products

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Recombinant Human BH3 Interacting Domain Death Agonist, His-tagged

Cat. No.: BID-2427H
Product Overview: Recombinant human truncated C-terminal Bid (aa 61-195) produced inE. coliis fused at the N-terminus to a His-tag.
Description: Bid is an abundant pro-apoptotic protein of the Bcl-2 family that is crucial for death receptor-mediated apoptosis in many cell systems. Bid action has been proposed to involve the mitochondrial re-location of its truncated from tBid, to facilitate the release of apoptogenic proteins like cytochrome c.
Source/Host: E. coli.
Concentration: 0.5mg/ml.
Purity: ≥95% (SDS-PAGE). Affinity purified.
Biological Activity: Facilitates Bax oligomerization and induces cytochrome c release in isolated mitochondria (10-50ng/ml).
Application: Studies of Bid/Bax interaction and in vitro cytochrome c release.
Formulation: Liquid. In PBS.
Long Term Storage: -80°C.
Gene Name: BID BH3 interacting domain death agonist [ Homo sapiens ]
Synonyms: BID; BH3 interacting domain death agonist; FP497; MGC15319; MGC42355; BID isoform Si6; BID isoform L(2); BID isoform ES(1b); OTTHUMP00000196197; desmocollin type 4; apoptic death agonist; Human BID coding sequence; BH3-interacting domain death agonist; p22 BID
Gene ID: 637
mRNA Refseq: NM_001196
Protein Refseq: NP_001187
MIM: 601997
UniProt ID: P55957
Chromosome Location: 22q11.1
Pathway: Apoptosis; Natural killer cell mediated cytotoxicity; Apoptosis
Function: death receptor binding; protein binding

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