Cat. No. :	Thy1-2430M
Product Overview :	Recombinant extracellular domain of mouse Thy-1 (aa 20-131) produced inHEK 293 cellsis fused to the Fc portion of human IgG1. The integrin binding sequence RLD of mouse Thy-1 has been changed to RLE abolishing the binding of integrins, 48kDa (SDS-PAGE).
Description :	Thy-1 is a glycosyl phosphatidylinositol (GPI)-anchored glycoprotein of the immunoglobulin superfamily expressed in various cell types, particularly in cells of the neuronal system, activited microvascular endothelial cells, fibroblasts and blood stem cells. Thy-1 is involved in cell adhesion. Thy-1 interacts with the integrin avB3 (CD51/CD61) and Mac-1 (CD11b/CD18). In astrocytes, binding of Thy-1 to β3-integrin promotes focal adhesion formation.
Source/Host :	HEK 293 cells.
Concentration :	1mg/ml after reconstitution.
Purity :	≥90% (SDS-PAGE).
Endotoxin Content :	<0.1EU/µg purified protein (LAL test; Bio Whittaker).
Reconstitution :	Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
Formulation :	Lyophilized. Contains PBS.
Long Term Storage :	-20°C.
Use/Stability :	Stable for at least 6 months after receipt when stored at -20°C.
Handling :	Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

Gene Name :	Thy1 thymus cell antigen 1, theta [ Mus musculus ]
Synonyms :	thymus cell antigen 1, theta; T25; CD90; Thy-1; Thy1.1; Thy1.2; Thy-1.2; Thy1; Thy 1.2; ; theta; Thy 1.2; OTTMUSP00000018127
Gene ID :	21838
mRNA Refseq :	NM_009382
Protein Refseq :	NP_033408
UniProt ID :	P01831
Chromosome Location :	9 26.0 cM
Function :	Leukocyte transendothelial migration

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