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Recombinant Mouse Thymus Cell Antigen 1, Theta, Fc Chimera
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Cat. No. : | Thy1-2430M |
Product Overview : | Recombinant extracellular domain of mouse Thy-1 (aa 20-131) produced inHEK 293 cellsis fused to the Fc portion of human IgG1. The integrin binding sequence RLD of mouse Thy-1 has been changed to RLE abolishing the binding of integrins, 48kDa (SDS-PAGE). |
Description : | Thy-1 is a glycosyl phosphatidylinositol (GPI)-anchored glycoprotein of the immunoglobulin superfamily expressed in various cell types, particularly in cells of the neuronal system, activited microvascular endothelial cells, fibroblasts and blood stem cells. Thy-1 is involved in cell adhesion. Thy-1 interacts with the integrin avB3 (CD51/CD61) and Mac-1 (CD11b/CD18). In astrocytes, binding of Thy-1 to β3-integrin promotes focal adhesion formation. |
Source/Host : | HEK 293 cells. |
Concentration : | 1mg/ml after reconstitution. |
Purity : | ≥90% (SDS-PAGE). |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
Formulation : | Lyophilized. Contains PBS. |
Long Term Storage : | -20°C. |
Use/Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Handling : | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |
Gene Name : | Thy1 thymus cell antigen 1, theta [ Mus musculus ] |
Synonyms : | thymus cell antigen 1, theta; T25; CD90; Thy-1; Thy1.1; Thy1.2; Thy-1.2; Thy1; Thy 1.2; ; theta; Thy 1.2; OTTMUSP00000018127 |
Gene ID : | 21838 |
mRNA Refseq : | NM_009382 |
Protein Refseq : | NP_033408 |
UniProt ID : | P01831 |
Chromosome Location : | 9 26.0 cM |
Function : | Leukocyte transendothelial migration |
◆ Recombinant Protein
THY1-542H | Recombinant Human Thy1 Protein | +Inquiry |
THY1-657H | Recombinant Human THY1 Protein (Met1-Cys130), His-tagged | +Inquiry |
THY1-541H | Recombinant Human Thy1 Protein, Fc-tagged | +Inquiry |
THY1-586H | Recombinant Human THY1, Fc-tagged | +Inquiry |
Thy1-6911M | Recombinant Mouse Thy1 protein, His-tagged | +Inquiry |
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◆ Lysates
THY1-952CCL | Recombinant Cynomolgus THY1 cell lysate | +Inquiry |
THY1-1297RCL | Recombinant Rat THY1 cell lysate | +Inquiry |
THY1-2384MCL | Recombinant Mouse THY1 cell lysate | +Inquiry |
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