| Cat. No. : |
Thy1-2430M |
| Product Overview : |
Recombinant extracellular domain of mouse Thy-1 (aa 20-131) produced inHEK 293 cellsis fused to the Fc portion of human IgG1. The integrin binding sequence RLD of mouse Thy-1 has been changed to RLE abolishing the binding of integrins, 48kDa (SDS-PAGE). |
| Description : |
Thy-1 is a glycosyl phosphatidylinositol (GPI)-anchored glycoprotein of the immunoglobulin superfamily expressed in various cell types, particularly in cells of the neuronal system, activited microvascular endothelial cells, fibroblasts and blood stem cells. Thy-1 is involved in cell adhesion. Thy-1 interacts with the integrin avB3 (CD51/CD61) and Mac-1 (CD11b/CD18). In astrocytes, binding of Thy-1 to β3-integrin promotes focal adhesion formation. |
| Source/Host : |
HEK 293 cells. |
| Concentration : |
1mg/ml after reconstitution. |
| Purity : |
≥90% (SDS-PAGE). |
| Endotoxin Content : |
<0.1EU/µg purified protein (LAL test; Bio Whittaker). |
| Reconstitution : |
Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
| Formulation : |
Lyophilized. Contains PBS. |
| Long Term Storage : |
-20°C. |
| Use/Stability : |
Stable for at least 6 months after receipt when stored at -20°C. |
| Handling : |
Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.