"TNFRSF19" Related Products

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Recombinant Human TNFRSF19, Fc Chimera

Cat. No. : TNFRSF19-2435H
Product Overview : Recombinant cysteine-rich domain of human Troy (TAJ) (aa 1-168) produced inHEK 293 cellsis fused to the Fc portion of human IgG1. 48kDa (under reducing conditions).
Description : Troy, or TAJ, is a member of the tumor necrosis factor receptor (TNFR) family. Troy plays a role in axonal regeneration by forming a functional receptor complex with Nog-66 receptor 1 and LINGO-1. This receptor complex binds myelin inhibitors (Nogo-A, myelin.associated glycoprotein (MAG), oligodendrocyte myelin glycoprotein (OMgp) and signals myelin inhibition by activating RhoA. Troy also interacts with TRAF proteins and activates JNK.
Source/Host : HEK 293 cells.
Concentration : 1mg/ml after reconstitution.
Purity : ≥90% (SDS-PAGE).
Endotoxin Content : <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Reconstitution : Reconstitute in 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum.
Formulation : Lyophilized. Contains PBS.
Long Term Storage : -20°C.
Use/Stability : Stable for at least 6 months after receipt when stored at -20°C. Once reconstituted, it is recommended to prepare appropriate aliquots and to store them at -20°C.
Handling : Avoid freeze/thaw cycles.
Gene Name : TNFRSF19 tumor necrosis factor receptor superfamily, member 19 [ Homo sapiens ]
Synonyms : tumor necrosis factor receptor superfamily, member 19; TAJ; TROY; TRADE; TAJ-alpha; TNFRSF19; tumor necrosis factor receptor superfamily member 19; toxicity and JNK inducer; Toxicity and JNK inducer; OTTHUMP00000018114
Gene ID : 55504
mRNA Refseq : NM_018647
Protein Refseq : NP_061117
MIM : 606122
UniProt ID : Q9NS68
Chromosome Location : 13q12.11-q12.3
Pathway : Cytokine-cytokine receptor interaction
Function : protein binding; receptor activity; tumor necrosis factor receptor activity

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