Recombinant Mouse Tnfsf12, FLAG-tagged
Cat.No. : | Tnfsf12-196M |
Product Overview : | Recombinant Mouse Tnfsf12 isproduced inHEK 293 cells.The extracellular domain of mouse TWEAK (aa 94-249) is fused at the N-terminus to tenascin-C (TNC) (chicken) (aa 110-139) and a FLAG-tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Tnfsf12-196M |
Description : | Some TNF ligands (such as TWEAK (mouse) or FasL (mouse)) produced as soluble forms do not assemble into stable trimers and show low receptor binding. Addition of the tenascin-C oligomerization domain (TNC) (from chicken) at the N-terminus of recombinant mouse soluble TWEAK stabilizes the TNF homology domain (THD) of rmsTWEAK into a trimer and increases binding to its respective TNF receptor. |
Source : | HEK 293 cells. |
Purity : | ≥95% (SDS-PAGE). |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Concentration : | 0.1mg/ml after reconstitution. |
Formulation : | Lyophilized. Contains PBS. |
Reconstitution : | Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein. |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Long term storage: -20°C, short term storage: +4°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Gene Name : | Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 [ Mus musculus ] |
Synonyms : | Tnfsf12; tumor necrosis factor (ligand) superfamily, member 12; DR3L; APO3L; DR3LG; Tweak; tumor necrosis factor ligand superfamily member 12; OTTMUSP00000006216; TNF-related weak inducer of apoptosis |
Gene ID : | 21944 |
mRNA Refseq : | NM_011614 |
Protein Refseq : | NP_035744 |
UniProt ID : | O54907 |
Chromosome Location : | 11 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | cytokine activity; tumor necrosis factor receptor binding |
Products Types
◆ Recombinant Protein | ||
TNFSF12-9483M | Recombinant Mouse TNFSF12 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tnfsf12-86M | Active Recombinant Mouse Tnfsf12 Protein (His110-His249), C-His tagged, Animal-free, Carrier-free | +Inquiry |
TNFSF12-810M | Recombinant Mouse TNFSF12 Protein (Arg105-His249), RlgG Fc-tagged | +Inquiry |
TNFSF12-01H | Recombinant Human TNFSF12 Protein, His/FLAG-tagged | +Inquiry |
TNFSF12-200T | Active Recombinant Human TNFSF12 Protein | +Inquiry |
◆ Lysates | ||
TNFSF12-1155CCL | Recombinant Cynomolgus TNFSF12 cell lysate | +Inquiry |
TNFSF12-1204RCL | Recombinant Rat TNFSF12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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