Recombinant Human Phospholipase D2 PLD2-683H

Recombinant Human Phospholipase D2


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Recombinant Human Phospholipase D2

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Cat. No. : PLD2-683H
Product Overview : Recombinant human PLD2 (aa 1-274) is expressed inE. coli. MW=56kDa.
Description : Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.
Source : E. coli.
Application : ELISA, Inhibition Assays, Western Blotting.
Presentation : 100μl purified human PLD2 protein at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
Characterization : On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 56kDa (including GST).
Storage : Store vial at -200C to -80℃. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name : PLD2 phospholipase D2 [ Homo sapiens ]
Synonyms : PLD2; phospholipase D2; EC; PLD 2; PLD1C; choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2
Gene ID : 5338
mRNA Refseq : NM_002663
Protein Refseq : NP_002654
MIM : 602384
UniProt ID : O14939
Chromosome Location : 17p13.1
Pathway : Endocytosis; Ether lipid metabolism; Fc gamma R-mediated phagocytosis; Glycerophospholipid metabolism; GnRH signaling pathway; Metabolic pathways
Function : NAPE-specific phospholipase D activity; hydrolase activity; phosphoinositide binding; phospholipase D activity; protein binding

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