Recombinant Rat Ren protein, His-tagged

• Cat.No.: Ren-695R
• Product Overview: Recombinant Rat Ren(65–402 aa) fused with His tag at C-terminal was expressed in HEK293.

Specification

• Description: Renin is a protease that is synthesized by the kidneys. Renin catalyzes the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the treatment of hypertension (high blood pressure).
• Source: HEK293
• Species: Rat
• Tag: His
• Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
• Molecular Mass: 38.5 kDa
• Purity: >90%
• Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 1.26 mg/ml

Gene Information

• Gene Name: Ren renin [ Rattus norvegicus ]
• Official Symbol: Ren
• Synonyms: REN; renin; angiotensinogenase; renin 1 structural; Ren1; RENAA; RATRENAA
• Gene ID: 24715
• mRNA Refseq: NM_012642
• Protein Refseq: NP_036774
• UniProt ID: P08424
• Chromosome Location: 13q13
• Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Renin - Angiotensin System, organism-specific biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem
• Function: aspartic-type endopeptidase activity; aspartic-type endopeptidase activity; endopeptidase activity; endopeptidase activity; insulin-like growth factor receptor binding; peptidase activity; peptidase activity; receptor binding; receptor binding