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Recombinant Rat Ren protein, His-tagged

Cat.No.: Ren-695R
Product Overview: Recombinant Rat Ren(65–402 aa) fused with His tag at C-terminal was expressed in HEK293.
Description: Renin is a protease that is synthesized by the kidneys. Renin catalyzes the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the treatment of hypertension (high blood pressure).
Source: HEK293
Species: Rat
Tag: His
Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Molecular Mass: 38.5 kDa
Purity: >90%
Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles.
Concentration: 1.26 mg/ml
Gene Name: Ren renin [ Rattus norvegicus ]
Official Symbol: Ren
Synonyms: REN; renin; angiotensinogenase; renin 1 structural; Ren1; RENAA; RATRENAA;
Gene ID: 24715
mRNA Refseq: NM_012642
Protein Refseq: NP_036774
MIM:
UniProt ID: P08424
Chromosome Location: 13q13
Pathway: ACE Inhibitor Pathway, organism-specific biosystem; Renin - Angiotensin System, organism-specific biosystem; Renin-angiotensin system, organism-specific biosystem; Renin-angiotensin system, conserved biosystem;
Function: aspartic-type endopeptidase activity; aspartic-type endopeptidase activity; endopeptidase activity; endopeptidase activity; insulin-like growth factor receptor binding; peptidase activity; peptidase activity; receptor binding; receptor binding;

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