Recombinant Human Ribonuclease H2, Subunit A

• Cat.No.: RNASEH2A-76H
• Product Overview: Recombinant Human Ribonuclease H2, Subunit A is expressed inE. coli.

Specification

• Cat. No.: RNASEH2A-76H
• Description: The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes.
• Source: E. coli.
• Purity: > 95%.
• Concentration: 2 x 105 units/ml, 100 μl.
• Form: Stored in PBS buffer with 0.1% BSA.
• Storage: -70oC. Keep Freeze thaw to a minimum. Dilute only in buffers containing protein such as 0.1% BSA, Dilution of material below 2 x105 units/ml is not recommended.

Gene Information

• Gene Name: RNASEH2A ribonuclease H2, subunit A [ Homo sapiens ]
• Synonyms: RNASEH2A; ribonuclease H2, subunit A; AGS4; JUNB; RNHL; RNHIA; RNASEHI; EC 3.1.26.4; ribonuclease H2 subunit A; RNase H(35); RNase H2 subunit A; ribonuclease HI subunit A; ribonuclease H2, large subunit; aicardi-Goutieres syndrome 4 protein
• Gene ID: 10535
• mRNA Refseq: NM_006397
• Protein Refseq: NP_006388
• MIM: 606034
• UniProt ID: O75792
• Chromosome Location: 19p13.2
• Pathway: DNA replication
• Function: RNA binding; endonuclease activity; hydrolase activity; metal ion binding; ribonuclease H activity; ribonuclease activity