"QPRT" Related Products

Recombinant Human QPRT, T7-tagged

Cat. No.: QPRT-2954H
Product Overview: Recombinant Human QPRT was produced inE.coliwith a T7 tag at N-terminus. MW = 30816 Da (1-297 aa).
Description: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer"s disease, and Huntington"s disease.
Source: E.coli.
Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
Purity: 95%.
Applications: MS. SDS.
Gene Name: QPRT quinolinate phosphoribosyltransferase [ Homo sapiens ]
Synonyms: QPRT; quinolinate phosphoribosyltransferase; QPRTase; nicotinate-nucleotide pyrophosphorylase [carboxylating]; QAPRTase; nicotinate-nucleotide pyrophosphorylase (carboxylating); EC 2.4.2.19; nicotinate-nucleotide pyrophosphorylase
Gene ID: 23475
mRNA Refseq: NM_014298
Protein Refseq: NP_055113
MIM: 606248
UniProt ID: Q15274
Chromosome Location: 16p11.2
Pathway: Metabolic pathways; Nicotinate and nicotinamide metabolism
Function: nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein homodimerization activity; transferase activity, transferring glycosyl groups

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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