Recombinant Human MAPK Scaffold Protein 1, His-tagged

• Cat.No.: MAPKSP1-937H
• Product Overview: Recombinant human MAPKSP1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 15.8kDa (144aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MAPKSP1 (Mitogen-activated protein kinase scaffold protein 1) is a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 5mM DTT, 100mM NaCl.
• Purity: > 95% by SDS - PAGE.
• Concentration: 0.5mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: GSSHHHHHH SSGLVPRGSH MADDLKRFLY KKLPSVEGLH AIVVSDRDGV PVIK VANDNA PEHALRPGFL STFALATDQG SKLGLSKNKSIICYYNTYQV VQFNRLPLVV SFIASSSANT GLIVSLEKEL APLFEELRQV VEVS.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: MAPK signaling pathway

Gene Information

• Gene Name: MAPKSP1 MAPK scaffold protein 1 [ Homo sapiens ]
• Synonyms: MAPK scaffold protein 1; MP1; MAPBP; MAP2K1IP1; MAPKSP1; PRO0633; mitogen-activated protein kinase scaffold protein 1; MEK partner 1; OTTHUMP00000219461; MEK binding partner 1; MEK-binding partner 1; mitogen-activated protein kinase kinase 1 interacting protein 1; mitogen-activated protein kinase kinase 1-interacting protein 1; Mitogen-activated protein kinase kinase 1-interacting protein 1; Mp1
• Gene ID: 8649
• mRNA Refseq: NM_021970
• Protein Refseq: NP_068805
• MIM: 603296
• UniProt ID: Q9UHA4
• Chromosome Location: 4q23
• Function: protein binding