||Recombinant human MAPKSP1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 15.8kDa (144aa).
||MAPKSP1 (Mitogen-activated protein kinase scaffold protein 1) is a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.
||Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 5mM DTT, 100mM NaCl.
||> 95% by SDS - PAGE.
||0.5mg/ml (determined by Bradford assay).
|Sequences Of Amino Acids:
||GSSHHHHHH SSGLVPRGSH MADDLKRFLY KKLPSVEGLH AIVVSDRDGV PVIK VANDNA PEHALRPGFL STFALATDQG SKLGLSKNKSIICYYNTYQV VQFNRLPLVV SFIASSSANT GLIVSLEKEL APLFEELRQV VEVS.
||Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
||MAPK signaling pathway