Active Recombinant Human ANGPT2, Flag-tagged
Cat.No. : | ANGPT2-435H |
Product Overview : | Recombinant Human ANGPT2(aa 19-496), fused at the N-terminus to a FLAG®-tag, was expressed in HEK 293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. |
Source : | HEK 293 cells |
Species : | Human |
Tag : | Flag |
Form : | Lyophilized. Contains PBS with trehalose and Brij35. |
Bio-activity : | Binds to the human and mouse Tie-2 receptor. |
Molecular Mass : | ~70kDa (SDS-PAGE) |
Endotoxin : | <0.01EU/μg purified protein (LAL test; Lonza). |
Purity : | ≥95% (SDS-PAGE) |
Storage : | Short Term Storage: +4°CLong Term Storage: -20°CHandling Advice: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 0.1 mg /ml after reconstitution. |
Reconstitution : | Reconstitute with 100μl sterile water. |
Gene Name : | ANGPT2 angiopoietin 2 [ Homo sapiens ] |
Official Symbol : | ANGPT2 |
Synonyms : | ANGPT2; angiopoietin 2; ANG2; AGPT2; Tie2-ligand; angiopoietin-2B;.angiopoietin-2a; angiopoietin-2; ANG-2 |
Gene ID : | 285 |
mRNA Refseq : | NM_001118887 |
Protein Refseq : | NP_001112359 |
MIM : | 601922 |
UniProt ID : | O15123 |
Chromosome Location : | 8p23.1 |
Pathway : | Angiopoietin receptor Tie2-mediated signaling; Cell surface interactions at the vascular wall; HIF-1 signaling pathway |
Function : | metal ion binding; protein binding; receptor binding; receptor tyrosine kinase binding |
Products Types
◆ Recombinant Protein | ||
ANGPT2-1173C | Active Recombinant Cynomolgus ANGPT2 Protein, His-tagged | +Inquiry |
ANGPT2-484H | Recombinant Human ANGPT2 Protein | +Inquiry |
ANGPT2-01P | Recombinant Pig ANGPT2 Protein, N-His tagged | +Inquiry |
ANGPT2-3182H | Active Recombinant Human ANGPT2 protein(Met1-Phe496), His-tagged | +Inquiry |
ANGPT2-325R | Recombinant Rat ANGPT2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ANGPT2-001MCL | Recombinant Mouse ANGPT2 cell lysate | +Inquiry |
ANGPT2-2228HCL | Recombinant Human ANGPT2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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