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Recombinant Human ATP5O, 24-213 aa, His-tagged

Cat.No. : ATP5O-950H
Product Overview : Recombinant human ATP5O protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 23.1 kDa (211aa).
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  • Gene Information
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Cat. No. : ATP5O-950H
Description : ATP synthase subunit O, also known as ATP5O, localizes to the mitochondria and catalyzes ATP synthesis. The protein is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane proton channel. The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.2M NaCl.
Purity : > 95% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MFAKLVRPPV QVYGIEGRYA TALYSAASKQ NKLEQVEKEL LRVAQILKEP KVAASVLNPY VKRSIKVKSL NDITAKERFS PLTTNLINLL AENGRLSNTQ GVVSAFSTMM SVHRGEVPCT VTSASPLEEA TLSELKTVLK SFLSQGQVLK LEAKTDPSIL GGMIVRIGEK YVDMSVKTKI QKLGRAMREI V.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways : Alzheimer"s disease; Huntington"s disease; Metabolic pathways; Oxidative phosphorylation; Parkinson"s disease; Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins
Gene Name : ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit [ Homo sapiens ]
Synonyms : ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; ATPO; OSCP; ATP5O;ATP synthase subunit O, mitochondrial; human ATP synthase OSCP subunit; oligomycin sensitivity conferral protein; oligomycin sensitivity conferring protein; Oligomycin sensitivity conferral protein; human ATP synthase OSCP subunit, oligomycin sensitivity conferring protein9
Gene ID : 539
mRNA Refseq : NM_001697
Protein Refseq : NP_001688
MIM : 600828
UniProt ID : P48047
Chromosome Location : 21q22.1-q22.2; 21q22.11
Function : contributes_to ATPase activity; drug binding; hydrogen ion transporting ATP synthase activity, rotational mechanism; transmembrane transporter activity; transporter activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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