Recombinant Human COCH, His tagged
Cat.No. : | COCH-3207H |
Product Overview : | Recombinant Human COCH (NP_001128530.1) mature form (Glu 25-Gln 550), fused with a polyhistidine tag at the N-terminus, was produced in Human Cell. |
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Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4 |
Molecular Mass : | The recombinant full length of human COCH consists of 542 amino acids and has a calculated molecular mass of 59.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCOCH is approximately 18 kDa, corresponding to the alternative splicing short isoform, whivch lacks two VWFA domains. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | COCH coagulation factor C homolog, cochlin (Limulus polyphemus) [ Homo sapiens ] |
Official Symbol : | COCH |
Gene ID : | 1690 |
mRNA Refseq : | NM_001135058 |
Protein Refseq : | NP_001128530 |
MIM : | 603196 |
UniProt ID : | O43405 |
Products Types
◆ Recombinant Protein | ||
COCH-1840M | Recombinant Mouse COCH Protein, His (Fc)-Avi-tagged | +Inquiry |
COCH-1619H | Recombinant Human COCH Protein, GST-tagged | +Inquiry |
COCH-781R | Recombinant Rhesus Macaque COCH Protein, His (Fc)-Avi-tagged | +Inquiry |
COCH-1119Z | Recombinant Zebrafish COCH | +Inquiry |
COCH-6497C | Recombinant Chicken COCH | +Inquiry |
◆ Lysates | ||
COCH-2373HCL | Recombinant Human COCH cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMutations in COCH can lead to impaired cochlear function, resulting in hearing and balance disorders.
It plays a key role in the structural integrity and mechanical properties of the cochlear extracellular matrix.
COCH works with other cochlear proteins to maintain the mechanics and signal transduction necessary for hearing.
Therapeutic strategies targeting COCH could offer new treatments for genetic and age-related hearing loss.
COCH dysfunction is associated with the progression of age-related hearing loss, affecting cochlear homeostasis.
COCH is essential for maintaining the structure and function of the cochlea, crucial for hearing.
COCH dysfunctions are closely linked to various types of hearing loss, including sensorineural hearing loss.
Customer Reviews (3)
Write a reviewKey contributor to our research discoveries.
Swift and accurate service, a research necessity.
Invaluable support for our protein experiments.
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