Recombinant Human dCMP Deaminase, His-tagged
Cat.No. : | DCTD-732H |
Product Overview : | Recombinant human DCTD protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 22.1 kDa (198aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | DCTD-732H |
Description : | DCTD (deoxycytidylate deaminase), also known as dCMP deaminase, is a 178 amino acid allosteric enzyme that exists as a homohexamer and belongs to the cytidine and deoxycytidylate deaminase protein family. Using zinc as a cofactor, DCTD catalyzes the deamination of dCMP to dUMP, thereby producing the nucleotide substrate (dUMP) that is used by thymidylate synthase. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MSEVSCKKRD DYLEWPEYFM AVAFLSAQRS KDPNSQVGAC IVNSENKIVG IGYNGMPNGC SDDVLPWRRT AENKLDTKYP YVCHAELNAI MNKNSTDVKG CSMYVALFPC NECAKLIIQA GIKEVIFMSD KYHDSDEATA ARLLFNMAGV TFRKFIPKCS KIVIDFDSIN SRPSQKLQ |
Purity : | > 90% by SDS – PAGE. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 20% glycerol. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | DCTD dCMP deaminase [ Homo sapiens ] |
Synonyms : | DCTD; dCMP deaminase; MGC111062; deoxycytidylate deaminase; EC 3.5.4.12 |
Gene ID : | 1635 |
mRNA Refseq : | NM_001012732 |
Protein Refseq : | NP_001012750 |
MIM : | 607638 |
UniProt ID : | P32321 |
Chromosome Location : | 4q35.1 |
Pathway : | Metabolic pathways; Pyrimidine metabolism |
Function : | dCMP deaminase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; metal ion binding; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
DCTD-1457R | Recombinant Rat DCTD Protein, His (Fc)-Avi-tagged | +Inquiry |
DCTD-2408H | Recombinant Human DCTD Protein, GST-tagged | +Inquiry |
Dctd-2480M | Recombinant Mouse Dctd Protein, Myc/DDK-tagged | +Inquiry |
DCTD-1019R | Recombinant Rhesus Macaque DCTD Protein, His (Fc)-Avi-tagged | +Inquiry |
DCTD-27366TH | Recombinant Human DCTD, His-tagged | +Inquiry |
◆ Lysates | ||
DCTD-7044HCL | Recombinant Human DCTD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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