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Recombinant Human CTHRC1, His tagged

Cat.No. : CTHRC1-3225H
Product Overview : Recombinant Human CTHRC1 (NP_612464.1) (Met 1-Lys 243), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The recombinant human CTHRC1 consists of 224 amino acids and has a predicted molecular mass of 24.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CTHRC1 is approximately 28-33 kDa due to glycosylation.
Protein Length : Met 1-Lys 243
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 95 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Publication :
GPR180 is a component of TGFβ signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor CTHRC1 (2021)
Gene Name : CTHRC1 collagen triple helix repeat containing 1 [ Homo sapiens ]
Official Symbol : CTHRC1
Synonyms : CTHRC1; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1;
Gene ID : 115908
mRNA Refseq : NM_001256099
Protein Refseq : NP_001243028
MIM : 610635
UniProt ID : Q96CG8

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What factors regulate the expression and activity of CTHRC1 protein? 06/07/2023

Environmental factors, inflammatory responses, and mechanical stress can regulate the expression and activity of CTHRC1.

What role does CTHRC1 protein play in tissue repair and remodeling? 01/16/2021

CTHRC1 promotes cell migration and downregulates collagen synthesis in tissue repair, aiding in tissue remodeling.

How do structural changes in CTHRC1 protein affect its biological function? 01/11/2021

Structural changes in CTHRC1 may affect its interactions with the extracellular matrix and other proteins, altering its function.

How does the interaction of CTHRC1 protein with the Wnt signaling pathway affect cell proliferation and differentiation? 06/28/2020

The interaction of CTHRC1 with the Wnt signaling pathway influences cell proliferation and differentiation, especially in cancer and tissue repair.

What is the role of CTHRC1 protein in cardiovascular diseases? 04/01/2019

In cardiovascular diseases, CTHRC1 is involved in the remodeling and repair of blood vessels.

How does CTHRC1 protein affect the invasiveness and metastasis of cancer cells? 11/10/2018

CTHRC1 enhances cancer cell invasiveness and metastatic potential by facilitating extracellular matrix remodeling and signal transduction.

How does the expression level of CTHRC1 protein vary in different types of cancer? 07/11/2017

CTHRC1 expression is often increased in various cancers, associated with aggressiveness and severity of the disease.

Customer Reviews (3)

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Reviews
02/19/2023

    Consistent quality, a go-to for researchers.

    11/24/2018

      Expertise and professionalism in every analysis.

      06/22/2017

        Reliable support for our protein studies.

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