Recombinant Human Zinc finger protein 256, T7-tagged

• Cat.No.: ZNF256-3016H
• Product Overview: Recombinant Human ZNF256 protein was expressedwith N-terminal T7-tag in E.coli and purified by using conventional chromatography techniques, 54.9kDa (474aa).

Specification

• Cat. No.: ZNF256-3016H
• Description: The ZNF256 may function as a transcription factor and possesses transcriptional repressor activity in the KRAB domain. It belongs to the krueppel C2H2 type zinc finger protein family and contains 14 C2H2 type zinc fingers. ZNF256 interacts with a co-repressor protein, KRAB-associated protein 1 (KAP-1), through the KRAB domain and KAP-1 is necessary for ZNF256 function.
• Sequences of amino acids: MFLSSCTFEV SGKPFTCKEV GKDFLVRSRF LQQQAAHTRK KSNRTKSAVA FHSVKNHYNW GECVKAFSYK HVRVQHQGDL IRERSYMCSE CGKSFSTSCS LSDHLRVHTS EKPYTCGECG KSYRQSSSLI THRRIHTGVR PHQCDECGKL FNRKYDLLIH QRVHTGERPY KCSECGKSFS HSSSLITHQR IHTGMRPYEC SECGKSFIHS SSLITHQRVH TGTRPYMCSE CGKSFSQSCH LIKHRRLHIG EGPYECSECG KLFTYRSRFF QHQRVHTGVR SHECHECGKL FSRKFDLIVH ERVHTGERPY ECSECGKSFT CKSYLISHWK VHTGARPYEC GECGKSFTHS STLLQHQRVH TGERPYECNE CGKFFSQSSS LIRHRRSHTG ERPYECSECW KSFSNHSSLV KHRRVHTGER LYECSECGKS FSQSSNLTNH QRIHSGERPY ECSDCGKFFT FNSNLLKHQN VHKG
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT
• Purity: > 95% by SDS - PAGE

Gene Information

• Gene Name: ZNF256 zinc finger protein 256 [ Homo sapiens ]
• Synonyms: BMZF3; BMZF-3; Bone marrow zinc finger 3; Zinc finger protein 256
• Gene ID: 10172
• mRNA Refseq: NM_005773
• Protein Refseq: NP_005764
• MIM: 606956
• UniProt ID: Q9Y2P7
• Chromosome Location: 19q13.43
• Function: DNA binding; general transcriptional repressor activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding; a transcriptional repressor induced by GDNF that plays a role in cell proliferation