Recombinant Human Purine Nucleoside Phosphorylase, His-tagged
Cat.No. : | PNP-2872H |
Product Overview : | Recombinant human PNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PNP-2872H |
Description : | PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. |
Source : | E.coli. |
Sequence : | MGSSHHHHHH SSGLVPRGSH MENGYTYEDY KNTAEWLLSH TKHRPQVAII CGSGLGGLTD KLTQAQIFDY GEIPNFPRST VPGHAGRLVF GFLNGRACVM MQGRFHMYEG YPLWKVTFPV RVFHLLGVDT LVVTNAAGGL NPKFEVGDIM LIRDHINLPG FSGQNPLRGP NDERFGDRFP AMSDAYDRTM RQRALSTWKQ MGEQRELQEG TYVMVAGPSF ETVAECRVLQ KLGADAVGMS TVPEVIVARH CGLRVFGFSL ITNKVIMDYE SLEKANHEEV LAAGKQAAQK LEQFVSILMA SIPLPDKAS. |
Purity : | > 90% by SDS – PAGE. |
MW : | 34.2 kDa (309aa) confirmed by MALDI-TOF. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF. |
Concentration : | 1mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | PNP purine nucleoside phosphorylase [ Homo sapiens ] |
Synonyms : | PNP; purine nucleoside phosphorylase; FLJ94043, FLJ97288, FLJ97312, MGC117396, MGC125915, MGC125916, NP, PRO1837, PUNP; inosine phosphorylase; purine-nucleoside:orthophosphate ribosyltransferase |
Gene ID : | 4860 |
mRNA Refseq : | NM_000270 |
Protein Refseq : | NP_000261 |
MIM : | 164050 |
UniProt ID : | P00491 |
Chromosome Location : | 14q13.1 |
Pathway : | Metabolic pathways; Nicotinate and nicotinamide metabolism; Metabolism of nucleotides |
Function : | drug binding; nucleoside binding; purine-nucleoside phosphorylase activity |
Products Types
◆ Recombinant Protein | ||
PNP-1723H | Recombinant Human PNP Protein, His (Fc)-Avi-tagged | +Inquiry |
Pnp-4971M | Recombinant Mouse Pnp Protein, Myc/DDK-tagged | +Inquiry |
PNP-3312R | Recombinant Rhesus Macaque PNP Protein, His (Fc)-Avi-tagged | +Inquiry |
PNP-6887M | Recombinant Mouse PNP Protein, His (Fc)-Avi-tagged | +Inquiry |
PNP-2498H | Recombinant Human PNP protein(11-280 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
PNP-3071HCL | Recombinant Human PNP 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0711 | Purine Nucleoside Phosphorylase Activity Colorimetric Assay Kit | +Inquiry |
Kit-0712 | Purine Nucleoside Phosphorylase Activity Fluorometric Assay Kit | +Inquiry |
Kit-0877 | PNP Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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