"VAPB" Related Products

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Recombinant Human VAPB, His-tagged

Cat. No. : VAPB-2875H
Product Overview : Recombinant human VAPB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description : VAPB, also known as vesicle-associated membrane protein (VAMP)-associated protein B, is a type IV transmembrane protein and member of the VAP family of proteins. This protein may play a role in vesicle trafficking. It is found in plasma and intracellular vesicle membranes as a homodimer and heterodimer with VAPA, and interacts with VAMP1 and VAMP2. Defects in VAPB are a cause of amyotrophic lateral sclerosis type 8 and spinal muscular atrophy autosomal dominant Finkel type.
Source : E.coli.
Sequence : MGSSHHHHHH SSGLVPRGSH MAKVEQVLSL EPQHELKFRG PFTDVVTTNL KLGNPTDRNV CFKVKTTAPR RYCVRPNSGI IDAGASINVS VMLQPFDYDP NEKSKHKFMV QSMFAPTDTS DMEAVWKEAK PEDLMDSKLR CVFELPAEND KPHDVEINKI ISTTASKTET PIVSKSLSSS LDDTEVKKVM EECKRLQGEV QRLREENKQF KEEDGLRMRK TVQSNSPISA LAPTGKEEGL ST.
Purity : > 90% by SDS – PAGE.
MW : 27.1 kDa (242aa) confirmed by MALDI-TOF.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF.
Concentration : 1mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C [ Homo sapiens ]
Synonyms : VAPB; VAMP (vesicle-associated membrane protein)-associated protein B and C; RP5-1018E9.1, ALS8, VAMP-B, VAP-B; VAMP-associated 33 kDa protein; vesicle-associated membrane protein-associated protein B/C
Gene ID : 9217
mRNA Refseq : NM_001195677
Protein Refseq : NP_001182606
MIM : 605704
UniProt ID : O95292
Chromosome Location : 20q13.33
Pathway : Metabolism of lipids and lipoproteins
Function : beta-tubulin binding; enzyme binding; protein heterodimerization activity; structural molecule activity

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