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Recombinant Human PSMA1, T7-tagged

Cat.No. : PSMA1-839H
Product Overview : Recombinant Human PSMA1 was produced in E.coli with a T7 tag at N-terminus. MW = 29556Da (1-263 aa).
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Cat. No. : PSMA1-839H
Description : Proteasome subunit alpha type-1 is a protein that in humans is encoded by the PSMA1 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Source : E.coli.
Form : 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
Purity : 90%.
Clonality : N/A.
Applications : MS. SDS.
Gene Name : PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 [ Homo sapiens ]
Synonyms : PSMA1; proteasome (prosome, macropain) subunit, alpha type, 1; NU; HC2; PROS30; MGC1667; MGC14542; MGC14575; MGC14751; MGC21459; MGC22853; MGC23915; proteasome subunit alpha type-1; PROS-30; protein P30-33K; proteasome nu chain; macropain subunit C2; macropain subunit nu; proteasome subunit nu; 30 kDa prosomal protein; proteasome component C2; proteasome subunit, alpha-type, 1; multicatalytic endopeptidase complex subunit C2; EC 3.4.25.1
Gene ID : 5682
mRNA Refseq : NM_001143937
Protein Refseq : NP_001137409
MIM : 602854
UniProt ID : P25786
Chromosome Location : 11p15.1
Pathway : Proteasome
Function : RNA binding; peptidase activity; protein binding; threonine-type endopeptidase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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