Recombinant Human HDAC3, FLAG-tagged HDAC3-854H

Recombinant Human HDAC3, FLAG-tagged


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Recombinant Human HDAC3, FLAG-tagged

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Cat. No. : HDAC3-854H
Product Overview : Recombinant HumanHDAC3 is expressed in Baculovirus with a FLAG tag at N-terminus.
Description : The nucleosomal histones can be modified through reversible acetylation by histone acetyltransferases (HATs) and deacetylases (HDACs). Acetylation and deacetylation of histone proteins alters chromosome structure and affects transcription factor access to DNA. HDAC3 has an open reading frame of 428 amino acids. HDAC3 shares 53% amino acid identity with HDAC1 and 52% with HDAC2.
Source : Baculovirus.
Formulation : 1x dilution buffer A: 20 mM Tris-Cl (pH 8.0), 20% Glycerol, 100 mM KCl, 0.2 mM EDTA and 1mM DTT.
Application : Recombinant HDAC3 can be used 1) for in vitro function studies including transcription in the presence of co-factors such as N-CoR; 2) for protein-protein interaction assay; and 3) for cell growth assay.
Activity : 1 unit equals 1 nanogram of purified protein.
Gene Name : HDAC3 histone deacetylase 3 [ Homo sapiens ]
Synonyms :
HDAC3; ; histone deacetylase 3; RPD3; HD3; RPD3-2; EC; SMAP45
Gene ID : 8841
mRNA Refseq : NM_003883
Protein Refseq : NP_003874
MIM : 605166
UniProt ID : O15379
Chromosome Location : 5q31
Pathway : Signalling by NGF
Function : DNA binding; histone deacetylase activity; hydrolase activity; transcription factor binding

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