"GIPC1" Related Products

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Recombinant Human GIPC1, T7-tagged

Cat. No.: GIPC1-2897H
Product Overview: Recombinant HumanGIPC1 (1-333 aa) is expressed in E.Coli with a T7 tag at N-terminus.
Description: GIPC1 is a PDZ domain containing protein that interacts with RGS-GAIP and the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating Clathrin-coated vesicular trafficking. GIPC also associates with membrane bound Semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.
Source: E.Coli.
MW: 36049 Da.
Purity: 95%.
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
Application: MS. SDS.
Gene ID: 10755
mRNA Refseq: NM_005716
Protein Refseq: NP_005707
MIM: 605072
UniProt ID: O14908
Chromosome Location: 19p13.1
Function: PDZ domain binding; actin binding; myosin binding; protein binding; protein homodimerization activity; receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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