Recombinant Human Septin 2, His-tagged

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Recombinant Human Septin 2, His-tagged

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Cat. No. : SEPT2-2806H
Product Overview : Recombinant human Septin2 protein,fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 43.6 kDa (381aa), confirmed by MALDI-TOF.
Description : Septin2 (SEPT2) is a GTPase that is required for cytokinesis and associated with exocytosis. This protein can hetero-oligomerize with Septin6, 7 and also plays a role in the organization of new growth in organisms. It is associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments.
Source : E.coli.
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK STLINSLFLT DLYPERVISG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV DTPGYGDAIN CRDCFKTIIS YIDEQFERYL HDESGLNRRH IIDNRVHCCF YFISPFGHGL KPLDVAFMKA IHNKVNIVPV IAKADTLTLK ERERLKKRIL DEIEEHNIKI YHLPDAESDE DEDFKEQTRL LKASIPFSVV GSNQLIEAKG KKVRGRLYPW GVVEVENPEH NDFLKLRTML ITHMQDLQEV TQDLHYENFR SERLKRGGRK VENEDMNKDQ ILLEKEAELR RMQEMIARMQ AQMQMQMQGG DGDGGALGHH V
Purity : > 90% by SDS – PAGE.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl,1mM DTT.
Concentration : 0.25 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : SEPT2 septin 2 [ Homo sapiens ]
Synonyms : SEPT2; septin 2; DIFF6; NEDD5; Pnutl3; hNedd5; KIAA0158; septin-2; NEDD-5; OTTHUMP00000200248; OTTHUMP00000200249; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed developmentally down-regulated protein 5
Gene ID : 4735
mRNA Refseq : NM_001008491
Protein Refseq : NP_001008491
MIM : 601506
UniProt ID : Q15019
Chromosome Location : 2q37
Function : GTP binding; enzyme regulator activity; nucleotide binding; protein binding; protein complex scaffold
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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