Expand Expand| Cat. No. : | HPCAL1-2816H |
| Product Overview : | Recombinant human HPCAL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 24.4 kDa (213aa), confirmed by MALDI-TOF. |
| Description : | HPCAL1, also known as VILIP-3, is a member of neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein and nearly identical to the rat and mouse hippocalcin like-1 proteins. It is involved in the calcium-dependent regulation of rhodopsin phosphorylation and may be of relevance for neuronal signalling in the central nervous system. |
| Source : | E.coli. |
| Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MGKQNSKLRP EVLQDLRENT EFTDHELQEW YKGFLKDCPT GHLTVDEFKK IYANFFPYGD ASKFAEHVFR TFDTNGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISRSE MLEIVQAIYK MVSSVMKMPE DESTPEKRTD KIFRQMDTNN DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA SQF |
| Purity : | > 95% by SDS – PAGE. |
| Form : | Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl 1mM DTT, 10% glycerol. |
| Concentration : | 0.5 mg/ml (determined by Bradford assay). |
| Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
| PDB rendering based on 1bjf. : |
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| Gene Name : | HPCAL1 hippocalcin-like 1 [ Homo sapiens ] |
| Synonyms : | HPCAL1; hippocalcin-like 1; BDR1; HLP2; VILIP-3; HPCAL1; hippocalcin-like protein 1; visinin-like protein 3; calcium-binding protein BDR-1 |
| Gene ID : | 3241 |
| mRNA Refseq : | NM_002149 |
| Protein Refseq : | NP_002140 |
| MIM : | 600207 |
| UniProt ID : | P37235 |
| Chromosome Location : | 2p25.1 |
| Function : | calcium ion binding |
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