"EIF1AX" Related Products

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Recombinant Human EIF1AX, His-tagged

Cat. No.: EIF1AX-2817H
Product Overview: Recombinant human EIF1AX protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW =18.6kDa (164aa), confirmed by MALDI-TOF.
Description: EIF1AX is an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5" end of capped RNA. Itseems to be required for maximal rate of protein biosynthesis. And it enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA (I) to 40 S ribosomal subunits.
Source: E.coli.
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAM CFDGVKRLCH IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT FGPGDDDEIQ FDDIGDDDED IDDI
Purity: > 90% by SDS – PAGE.
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 5mM DTT, 200mM NaCl.
Concentration: 1mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: EIF1AX eukaryotic translation initiation factor 1A, X-linked [ Homo sapiens ]
Synonyms: EIF1AX; eukaryotic translation initiation factor 1A, X-linked; EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1; eIF-1A X isoform; OTTHUMP00000024301; eukaryotic translation initiation factor 4C; Putative eukaryotic translation initiation factor 1A; eukaryotic translation initiation factor 1A, X chromosome; Eukaryotic translation initiation factor 1A, X-chromosomal
Gene ID: 1964
mRNA Refseq: NM_001412
Protein Refseq: NP_001403
MIM: 300186
UniProt ID: P47813
Chromosome Location: Xp22.12
Pathway: Gene Expression; Metabolism of proteins
Function: RNA binding; translation factor activity, nucleic acid binding; translation initiation factor activity

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