"GUK1" Related Products

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Recombinant Human Guanylate Kinase 1, His-tagged

Cat. No. : GUK1-2785H
Product Overview : Recombinant human GUK1 protein (1-197aa), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : GUK1, also known as GMK, belongs to the guanylate kinase family. This protein exists as a monomer that catalyzes the ATP-dependent conversion of GMP to GDP, thereby playing an essential role in the recycling of GMP.
Source : E.coli.
Sequences : MGSSHHHHHH SSGLVPRGSH MSGPRPVVLS GPSGAGKSTL LKRLLQEHSG IFGFSVSHTT RNPRPGEENG KDYYFVTREV MQRDIAAGDF IEHAEFSGNL YGTSKVAVQA VQAMNRICVL DVDLQGVRNI KATDLRPIYI SVQPPSLHVL EQRLRQRNTE TEESLVKRLA AAQADMESSK EPGLFDVVII NDSLDQAYAE LKEALSEEIK KAQRTGA.
Form : Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol.
Molecular Weight : 23.9 kDa (217aa), confirmed by MALDI-TOF.
Purity : > 90% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : GUK1 guanylate kinase 1 [ Homo sapiens ]
Synonyms :
GUK1; guanylate kinase 1; GMP kinase; OTTHUMP00000037738; OTTHUMP00000037739; OTTHUMP00000037740; OTTHUMP00000037741; OTTHUMP00000037742; OTTHUMP00000037743; OTTHUMP00000037746; OTTHUMP00000037747; OTTHUMP00000037748; OTTHUMP00000037750; OTTHUMP00000037751; guanylate kinase
Gene ID : 2987
mRNA Refseq : NM_000858
Protein Refseq : NP_000849
MIM : 139270
UniProt ID : Q16774
Chromosome Location : 1q32-q41
Pathway : Metabolic pathways; Purine metabolism; Metabolism of nucleotides
Function : ATP binding;guanylate kinase activity;kinase activity;nucleotide binding;transferase activity

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