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Recombinant Human DIRAS1, His-tagged

Cat.No. : DIRAS1-2817H
Product Overview : Recombinant human DIRAS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 24.1 kDa (215aa), confirmed by MALDI-TOF.
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Cat. No. : DIRAS1-2817H
Description : DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form.
Source : E.coli.
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MPEQSNDYRV VVFGAGGVGK SSLVLRFVKG TFRDTYIPTI EDTYRQVISC DKSVCTLQIT DTTGSHQFPA MQRLSISKGH AFILVFSVTS KQSLEELGPI YKLIVQIKGS VEDIPVMLVG NKCDETQREV DTREAQAVAQ EWKCAFMETS AKMNYNVKEL FQELLTLETR RNMSLNIDGK RSGKQKRTDR VKGKC
Purity : > 95% by SDS – PAGE.
Form : Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol 1mM DTT, 0.1M NaCl, 1mM EDTA.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : DIRAS1 DIRAS family, GTP-binding RAS-like 1 [ Homo sapiens ]
Synonyms : DIRAS1; DIRAS family, GTP-binding RAS-like 1; RIG; GBTS1; Di-Ras1; FLJ42681; GTP-binding protein Di-Ras1; ras-related inhibitor of cell growth; small GTP-binding tumor suppressor 1; distinct subgroup of the Ras family member 1
Gene ID : 148252
mRNA Refseq : NM_145173
Protein Refseq : NP_660156
MIM : 607862
UniProt ID : O95057
Chromosome Location : 19p13.3
Function : GTP binding; GTPase activity; nucleotide binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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