|Product Overview :
||Recombinant human WEE1, C-terminal fragment, amino acids Q36-Y432, N-terminal GST-HIS6 fusion protein with a Thrombin cleavage site, expressed in Sf9 insect cells. Specific kinase activity (Pi transfer): 2 pmol/µg × min; ATP-KM: 1.6 µM.
||This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
|Molecular Mass :
||At -80 centigrade. For complete recovery, mix well and spin before use. Product must not be stored in diluted solutions, aliquots below 10 µL are not advisable. Avoid repeated freeze-thaw cycles!