"CDK16" Related Products

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Recombinant Human Cyclin-dependent Kinase 16, GST-His

Cat. No.: CDK16-710H
Product Overview: Recombinant Human CDK16, Amino acids R107-F496, mutationally activated: S153A, N-terminally fused to GST-HIS6-Thrombin cleavage site, was expressed inSf9 cells.MW = 74,943 Da.
Description: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Source: Baculovirus infected Sf9 cells.
Purification: One-step affinity purification using GSH-agarose.
Product Identity: PCTAIRE1 was confirmed as PCTAIRE1 by mass spectroscopy LC-ESI-MS/MS (Protagen AG, Germany).
Storage Buffer: 50 mM Tris-HCl, pH 8.0; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol.
Concentration: 0.731 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity: 1 pmol/μg×min.
Storage: -80°C. Avoid repeated freeze-thaw cycles!
Gene Name: CDK16 cyclin-dependent kinase 16 [ Homo sapiens ]
Synonyms: CDK16; cyclin-dependent kinase 16; PCTK1; PCTAIRE; FLJ16665; PCTAIRE1; PCTGAIRE; cell division protein kinase 16; PCTAIRE-motif protein kinase 1; serine/threonine-protein kinase PCTAIRE-1; EC 2.7.11.22; PCTAIRE protein kinase 1
Gene ID: 5127
mRNA Refseq: NM_001170460
Protein Refseq: NP_001163931
MIM: 311550
UniProt ID: Q00536
Chromosome Location: Xp11.3-p11.23
Function: ATP binding; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity

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