Recombinant Human PAK3, GST-His
Cat.No. : | PAK3-722H |
Product Overview : | RecombinantHuman PAK3, full length, amino acids M1-R544, N-terminally fused to GST-HIS6-Thrombin cleavage site, was expressed inSf9insect cells. MW = 90,588 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PAK3-722H |
Description : | PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. |
Source : | Baculovirus infected Sf9 cells. |
Purification : | One-step affinity purification using GSH-agarose. |
Product Identity : | PAK3 was confirmed as PAK3 by by mass spectroscopy LC-ESI-MS/MS (Protagen AG,Germany). |
Storage Buffer : | 50 mM HEPES-NaOH, pH 7.5; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol. |
Concentration : | 0.360 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein). |
Specific Activity : | 79 pmol/μg×min. |
Storage : | -80°C. Avoid repeated freeze-thaw cycles! |
Gene Name : | PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 [ Homo sapiens ] |
Synonyms : | PAK3; p21 protein (Cdc42/Rac)-activated kinase 3; bPAK; MRX30; MRX47; OPHN3; hPAK3; CDKN1A; PAK3beta; p21-activated kinase 3; beta-PAK; oligophrenin-3; OTTHUMP00000023856; p21 (CDKN1A)-activated kinase 3; serine/threonine-protein kinase PAK 3; EC 2.7.11.1 |
Gene ID : | 5063 |
mRNA Refseq : | NM_001128166 |
Protein Refseq : | NP_001121638 |
MIM : | 300142 |
UniProt ID : | O75914 |
Chromosome Location : | Xq23 |
Pathway : | Axon guidance; ErbB signaling pathway; Focal adhesion; Regulation of actin cytoskeleton; Renal cell carcinoma; T cell receptor signaling pathway; Axon guidance |
Function : | ATP binding; collagen binding; nucleotide binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
PAK3-1105H | Recombinant Human PAK3 Protein (M1-R559), GST tagged | +Inquiry |
PAK3-1104H | Recombinant Human PAK3 Protein (M1-R559), Tag Free | +Inquiry |
PAK3-3923R | Recombinant Rat PAK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PAK3-36H | Recombinant Active Human PAK3 Protein (Full length), N-GST-tagged | +Inquiry |
PAK3-4261R | Recombinant Rat PAK3 Protein | +Inquiry |
◆ Lysates | ||
PAK3-517HCL | Recombinant Human PAK3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All PAK3 Products
Required fields are marked with *
My Review for All PAK3 Products
Required fields are marked with *
0
Inquiry Basket