"PAK6" Related Products

Recombinant Human PAK6, GST-His

Cat. No.: PAK6-724H
Product Overview: Recombinant Human PAK6, full length, amino acids M1-C681, N-terminally fused to GST-HIS6-Thrombin cleavage site, expressed inSf9insect cells. MW = 104,780 Da.
Description: PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.
Source: Baculovirus infected Sf9 cells.
Purification: One-step affinity purification using GSH-agarose.
Product Identity: PAK6 was confirmed as PAK6 by mass spectroscopy LC-ESI-MS/MS (Protagen AG, Germany).
Storage Buffer: 50 mM HEPES-NaOH, pH 7.5; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol.
Concentration: 0.082 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity: 7 pmol/μg×min.
Storage: -80°C. Avoid repeated freeze-thaw cycles!
Gene Name: PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 [ Homo sapiens ]
Synonyms: PAK6; p21 protein (Cdc42/Rac)-activated kinase 6; PAK5; p21-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated protein kinase 6; EC 2.7.11.1
Gene ID: 56924
mRNA Refseq: NM_001128628
Protein Refseq: NP_001122100
MIM: 608110
UniProt ID: Q9NQU5
Chromosome Location: 15q14
Pathway: Axon guidance; ErbB signaling pathway; Focal adhesion; Regulation of actin cytoskeleton; Renal cell carcinoma; T cell receptor signaling pathway
Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

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