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Recombinant Human PAK6, GST-His

Cat.No. : PAK6-724H
Product Overview : Recombinant Human PAK6, full length, amino acids M1-C681, N-terminally fused to GST-HIS6-Thrombin cleavage site, expressed inSf9insect cells. MW = 104,780 Da.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : PAK6-724H
Description : PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.
Source : Baculovirus infected Sf9 cells.
Purification : One-step affinity purification using GSH-agarose.
Product Identity : PAK6 was confirmed as PAK6 by mass spectroscopy LC-ESI-MS/MS (Protagen AG, Germany).
Storage Buffer : 50 mM HEPES-NaOH, pH 7.5; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol.
Concentration : 0.082 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity : 7 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 [ Homo sapiens ]
Synonyms : PAK6; p21 protein (Cdc42/Rac)-activated kinase 6; PAK5; p21-activated kinase 6; p21(CDKN1A)-activated kinase 6; p21-activated protein kinase 6; EC 2.7.11.1
Gene ID : 56924
mRNA Refseq : NM_001128628
Protein Refseq : NP_001122100
MIM : 608110
UniProt ID : Q9NQU5
Chromosome Location : 15q14
Pathway : Axon guidance; ErbB signaling pathway; Focal adhesion; Regulation of actin cytoskeleton; Renal cell carcinoma; T cell receptor signaling pathway
Function : ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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