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Recombinant Human Selectin L, His-tagged

Cat.No. : SELL-2678H
Product Overview : Recombinant Human Selectin L fused to an amino-terminal His tag is expressed inE. coli.
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  • Gene Information
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Cat. No. : SELL-2678H
Description : L-selectin, also known as CD62L, is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via the high endothelial venules. L-selectin is an effective marker for separating lymphoid progenitors from myeloid progenitors and hematopoietic stem cells in bone marrow.
Source : E. coli.
Purity : Greater than 95% (determined by SDS-PAGE and HPLC analysis).
Endotoxin Level : < 0.1 ng per μg of rHu APO-E4 (1EU/μg).
Formulation : Sterile-filtered, liquid formulation. L-selectin is supplied in 50% glycerol.
Applications : L-selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested.
Reconstitution : Please Note: Always centrifuge product before opening vial. The lyophilized protein should be reconstituted with distilled, sterile water to a concentration of 0.1-1.0 mg/ml. For further dilution, carrier protein (0.1% BSA or HSA) should be added to avoid loss of bioactivity.
Storage : The lyophilized protein, though stable at room temperature for up to 3 weeks, is best stored desiccated at -20°C. Reconstituted protein should be used immediately or stored long-term in undiluted working aliquots at -20°C. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze-thaw cycles.
Gene Name : SELL selectin L [ Homo sapiens ]
Synonyms :
SELL; selectin L; CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1; CD62 antigen-like family member L; L-selectin; gp90-MEL; leukocyte adhesion molecule-1; leukocyte surface antigen Leu-8; leukocyte-endothelial cell adhesion molecule 1; lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; CD62L antigen; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lymph node homing receptor
Gene ID : 6402
mRNA Refseq : NM_000655
Protein Refseq : NP_000646
MIM : 153240
UniProt ID : P14151
Chromosome Location : 1q23-q25
Pathway : Cell adhesion molecules (CAMs); Hemostasis; Signaling in Immune system
Function : glycosphingolipid binding; heparin binding; protein binding; sugar binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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