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Recombinant Human Natriuretic Peptides B, aa 1-76

Cat. No.: NPPB-2682H
Product Overview: Recombinant Human Natriuretic Peptides B (aa 1-76) is expressed inE. coli.
Description: BNP (Brain natriuretic peptide) is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. BNP is a 32 amino acid polypeptide and is co-secreted along with a 76 amino acid N-terminal fragment which is biologically inactive. This protein has biological actions including natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure.
Source: E. coli.
Sequence: APLGSPGSASD LETSGLQEQRN HLQGKLSELQVEQ TSLEPLQ ESPRPTGV WKSRE VATEGIRGHRK MVLYTLRAPR.
Purity: Over 95% pure by PAGE.
Buffer: 50 mM Tris, 100 mM NaCl, pH 7.4.
MW: 8390 Da.
Contents: 10 μg/100 μg (lyophilized).
Storage: 2-8 °C (lyophilized); - 20 °C (dissolved); Repeated thawing and freezing must be avoided.
Gene Name: NPPB natriuretic peptide precursor B [ Homo sapiens ]
Synonyms:
NPPB; Natriuretic peptides B; BNP; OTTHUMP00000002506; OTTHUMP00000044486; Gamma-brain natriuretic peptide; brain type natriuretic peptide; natriuretic peptide precursor B; natriuretic protein; Gamma-brain natriuretic peptide; GC-B
Gene ID: 4879
mRNA Refseq: NM_002521
Protein Refseq: NP_002512
MIM: 600295
UniProt ID: P16860
Chromosome Location: 1p36.2
Function: diuretic hormone activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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