Recombinant Human Natriuretic Peptides B, aa 1-76

• Cat.No.: NPPB-2682H
• Product Overview: Recombinant Human Natriuretic Peptides B (aa 1-76) is expressed inE. coli.

Specification

• Cat. No.: NPPB-2682H
• Description: BNP (Brain natriuretic peptide) is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. BNP is a 32 amino acid polypeptide and is co-secreted along with a 76 amino acid N-terminal fragment which is biologically inactive. This protein has biological actions including natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure.
• Source: E. coli.
• Sequence: APLGSPGSASD LETSGLQEQRN HLQGKLSELQVEQ TSLEPLQ ESPRPTGV WKSRE VATEGIRGHRK MVLYTLRAPR.
• Purity: Over 95% pure by PAGE.
• Buffer: 50 mM Tris, 100 mM NaCl, pH 7.4.
• MW: 8390 Da.
• Contents: 10 μg/100 μg (lyophilized).
• Storage: 2-8 °C (lyophilized); - 20 °C (dissolved); Repeated thawing and freezing must be avoided.

Gene Information

• Gene Name: NPPB natriuretic peptide precursor B [ Homo sapiens ]
• Synonyms:
  NPPB; Natriuretic peptides B; BNP; OTTHUMP00000002506; OTTHUMP00000044486; Gamma-brain natriuretic peptide; brain type natriuretic peptide; natriuretic peptide precursor B; natriuretic protein; Gamma-brain natriuretic peptide; GC-B
• Gene ID: 4879
• mRNA Refseq: NM_002521
• Protein Refseq: NP_002512
• MIM: 600295
• UniProt ID: P16860
• Chromosome Location: 1p36.2
• Function: diuretic hormone activity