||Recombinant Human Natriuretic Peptides B (aa 1-108) is expressed inE. coli.
||BNP (Brain natriuretic peptide) is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. BNP is a 32 amino acid polypeptide and is co-secreted along with a 76 amino acid N-terminal fragment which is biologically inactive. This protein has biological actions including natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure.
||GRAPLGSPGSA SDLETSGLQEQRN HLQGKLSELQVEQTSLEPL QESPRPTG VWKSREVATEG IRGHRKMVLYT LRAPRSPKM VQGSGCFG RKMDRISSSS GLGCKVLRRHM.
||Over 95% pure by PAGE.
||50 mM Tris, 100 mM NaCl, pH 7.4.
||10 μg/100 μg (lyophilized).
||2-8 °C (lyophilized); - 20 °C (dissolved); Repeated thawing and freezing must be avoided.