"ICOSLG" Related Products

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Recombinant Human Inducible T-cell Co-stimulator Ligand, Fc Chimera

Cat. No.: ICOSLG-2143H
Product Overview: Recombinant human B7H2 extracellular domain (C-terminus fused with human IgG1 Fc)produced inmammalian cells contains 457amino acids with predicted MW 51.21D x 2 (dimmer), and 12 cysteines (Fc has 6). It also has 6 N-link glycosylation sites with MW increase up to 30 KD.
Description: B7H2 is ligand for the T-cell specific cell surface receptor ICOS and acts as a costimulatory signal for T-cell proliferation and differentiation. It induces also B-cell proliferation and differentiation in plasma cells.
Source: mammalian cells.
Purity: >90%.
Recommended Storage Temperature: -70°C.
Gene Name: ICOSLG inducible T-cell co-stimulator ligand [ Homo sapiens ]
Synonyms: inducible T-cell co-stimulator ligand; B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; KIAA0653; ICOSLG; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1; transmembrane protein B7-H2 ICOS ligand; B7-like protein; CD275 antigen
Gene ID: 23308
mRNA Refseq: NM_015259
Protein Refseq: NP_056074
MIM: 605717
UniProt ID: O75144
Chromosome Location: 21q22.3
Pathway: Cell adhesion molecules (CAMs); Intestinal immune network for IgA production; Signaling in Immune system
Function: receptor binding

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