"MME" Related Products

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Recombinant Human Membrane Metallo-endopeptidase, His-tagged

Cat. No.: MME-632H
Product Overview: Recombinant Human Membrane Metallo-endopeptidase is produced inSf9 cellsandfused at the N-terminus to a His-tag. MW= 85 kDa.
Description: MME, or 2,4-dimethoxy-5-ethoxyamphetamine, is a lesser-known psychedelic drug. It is a dimethoxy-ethoxy analog of TMA-2. MME was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 40 mg, and the duration listed as 6–10 hours. Shulgin gives MME a ++ on the Shulgin Rating Scale. Very little data exists about the pharmacological properties, metabolism, and toxicity of MME.
Source: Sf9 cell.
Concentration: 0.23 μg/μl.
Purity: ≥95% (SDS-PAGE).
Formulation: Liquid. In 50mM TRIS, pH 8.0. containing 300mM sodium chloride and 20% glycerol.
Specific Activity: 1140 pmol/min/μg.
Application: Study enzyme kinetics, cleave target substrates, and screen for inhibitors.
Storage And Stability: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
Gene Name: MME membrane metallo-endopeptidase [ Homo sapiens ]
Synonyms: MME; membrane metallo-endopeptidase; atriopeptidase; common acute lymphocytic leukemia antigen; enkephalinase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase); membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; neprilysin; neutral endopeptidase 24.11; EC 3.4.24.11
Gene ID: 4311
mRNA Refseq: NM_000902
Protein Refseq: NP_000893
MIM: 120520
UniProt ID: P08473
Chromosome Location: 3q25.1-q25.2
Pathway: Alzheimer"s disease; Hematopoietic cell lineage; Renin-angiotensin system
Function: metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; peptide binding; zinc ion binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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