GMP Recombinant Porcine IL17A Protein, His-Tagged

• Cat.No.: IL17A-01P
• Product Overview: GMP Recombinant Porcine IL17A Protein, His-Tagged was expressed in Escherichia coli cell-derived in an animal component free process under cGMP guidelines.

Specification

• Description: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).
• Source: Escherichia coli
• Species: Porcine
• Tag: His
• Form: Lyophilized
• AA Sequence: MGIMIPQSPGCPKTEDKNFPQHVRV NLNILNRSTPARRPSDYSKRSTSPW TLQRNEDPERYPSVIWEAKCSHSGC INAEGKEDHHMNSVPIQQEILVLRR EPRHCPNSFRLEKVMVTVGCTCVTP IVRHIS with polyhistidine tag at the C-terminus
• Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE. Ni-NTA chromatography
• Notes: Please use within one month after protein reconstitution.
• Storage: Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C.
• Storage Buffer: The protein was lyophilized from a solution containing 1X PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Gene Information

• Gene Name: IL17A interleukin 17A [ Sus scrofa (pig) ]
• Official Symbol: IL17A
• Synonyms: IL17
• Gene ID: 449530
• mRNA Refseq: NM_001005729.1
• Protein Refseq: NP_001005729.1
• UniProt ID: Q60I29