HDAC Inhibitor Drug Screening Kit (Fluorometric)
Cat.No. : | Kit-2347 |
Product Overview : | Inhibition of histone deacetylase (HDAC) has been implicated to modulate transcription and to induce apoptosis or differentiation in cancer cells. However, screening of compounds for HDAC inhibition has been difficult due to the lack of convenient tools for analyzing HDAC activity. The new HDAC Inhibitor Drug Screening Kit provides a fast, fluorescence-based method that eliminates radioactivity, extractions, or chromatography, as used in traditional assays. The new procedure requires only two easy steps, both performed on the same microtiter plate. First, your inhibitor candidates are mixed with HeLa Nuclear Extract and HDAC fluorometric substrate, which comprises an acetylated lysine side chain. Deacetylation of the substrate sensitizes the substrate, so that, in the second step, trea;ent with the Lysine Developer produces a fluorophore. The fluorophore can be easily analyzed using a fluorescence plate reader or a fluorometer. The assay is well suited for high throughput screening applications. |
- Specification
- Gene Information
- Related Products
Applications : | Screening of compounds for HDAC inhibition by analyzing HDAC activity |
Storage : | -80°C |
Size : | 100 assays |
Products Types
◆ Assay kits | ||
Kit-0425 | HDAC Activity/Inhibition Fluorometric Assay Kit | +Inquiry |
Kit-0983 | Fluorimetric HDAC Activity Assay Kit (Green) | +Inquiry |
Kit-0414 | HDAC fluorometric activity assay Kit | +Inquiry |
Kit-0423 | HDAC Activity Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All HDAC Products
Required fields are marked with *
My Review for All HDAC Products
Required fields are marked with *
0
Inquiry Basket