| Species : |
Human |
| Source : |
HT-1080 |
| Tag : |
Non |
| Description : |
This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. |
| Form : |
Cell-Tissue Lysis buffer |
| Molecular Mass : |
47 kDa |
| Notes : |
Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins. |
| Storage : |
Store at -20 centigrade for two years. |
| Concentration : |
Lot-specific |
| Shipping : |
Blue Ice |
| Components : |
1 vial of 100 μg WT HT-1080 cell lysate
1 vial of 100 μg ABRAXAS1 KD HT-1080 cell lysate |
| Lysate QC : |
RT-qPCR; Western Blotting (WB) |
