Human ACADVL Knockdown Cell Lysate

• Cat.No.: ACADVL-017HKCL
• Product Overview: WB-validated ACADVL Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 70 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg ACADVL KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Fatty acid metabolism, Metabolic pathways
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: ACADVL acyl-CoA dehydrogenase, very long chain [ Homo sapiens (human) ]
• Official Symbol: ACADVL
• Synonyms: ACADVL; acyl-CoA dehydrogenase, very long chain; acyl Coenzyme A dehydrogenase, very long chain; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD6; LCACD; VLCAD; acyl-Coenzyme A dehydrogenase, very long chain
• Gene ID: 37
• mRNA Refseq: NM_000018
• Protein Refseq: NP_000009
• MIM: 609575
• UniProt ID: P49748