Human AGO3 Knockdown Cell Lysate

• Cat.No.: AGO3-497HKCL
• Product Overview: WB-validated AGO3 Knockdown HT-1080 Cell Lysate

Specification

• Species: Human
• Source: HT-1080
• Tag: Non
• Description: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 97 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HT-1080 cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HT-1080 cell lysate 1 vial of 100 μg AGO3 KD HT-1080 cell lysate
• Protein Families: Druggable Genome
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: AGO3 argonaute RISC catalytic component 3 [ Homo sapiens (human) ]
• Official Symbol: AGO3
• Synonyms: AGO3; argonaute RISC catalytic component 3; EIF2C3; protein argonaute-3; argonaute 3, RISC catalytic component; eukaryotic translation initiation factor 2C, 3; hAgo3; EC 3.1.26.n2
• Gene ID: 192669
• mRNA Refseq: NM_024852
• Protein Refseq: NP_079128
• MIM: 607355
• UniProt ID: Q9H9G7